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. 2023 Jun 13;14:1195195. doi: 10.3389/fphar.2023.1195195

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Copyright © 2023 Liang, Tan, Du, Wang, Gao and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation of TCA cycle-based risk score with immune cell infiltration and immune checkpoint expression in ESCC patients. (A) Correlation plots of 22 tumor-infiltrating immune cells (TICs) in different patients was mapped by the seven algorithms. (B) Scatter plots of linear correlation between tumor purity and TCA cycle risk score. (C) Violin plots showing the distribution of immune score, ESTIMATE score, Stromal scores, and tumor purity in the TCA cycle high-risk and low-risk groups. (D) Box plot showing the difference in the expression of immune checkpoint genes between the two risk groups.