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. 2023 Jun 13;14:1195195. doi: 10.3389/fphar.2023.1195195

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Copyright © 2023 Liang, Tan, Du, Wang, Gao and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functions of CTTN in the ESCC cells. (A) The relative expression levels of CTTN mRNA in KYSE150 and TE-1 cells transfected with si-NC, si-CTTN-1 and si-CTTN-2. (B) Representative fluorescence images showing EdU assays in the si-NC, si-CTTN-1 and si-CTTN-2 groups. (C) The proliferation rates in the groups. (D) Representative images of colonies formed by cells transfected with si-NC, si-CTTN-1 and si-CTTN-2. (E) Number of colonies in the groups. (F) Representative images of transwell assays showing invasion of cells transfected with si-NC, si-CTTN-1 and si-CTTN-2. (G) Proportion of invading cells in the groups. (H) Protein expression of E-cadherin, Snail, Vimentin and N-cadherin in the groups. (I) The quantification of protein levels.