Table 2.
Independent association of triglyceride-glucose index and NT-proBNP categories with incident MACCEs
| Base Model† | Adjusted Model†† | |||
|---|---|---|---|---|
| Hazard Ratio (95% CI) | P Value | Hazard Ratio (95% CI) | P Value | |
| NT-proBNP | < 0.001 | < 0.001 | ||
| Tertile 1 | 1.00 (Reference) | 1.00 (Reference) | ||
| Tertile 2 | 1.53 (1.27‒1.86) | < 0.001 | 1.30 (1.04‒1.63) | 0.020 |
| Tertile 3 | 2.89 (2.41‒3.45) | < 0.001 | 1.95 (1.50‒2.54) | < 0.001 |
| TyG index, per 1 unit* | 1.16 (1.05‒1.27) | 0.002 | 1.18 (1.05‒1.32) | 0.004 |
*Modeled as linear effects
†Base model included the TyG index, NT-proBNP, age, and sex
††Adjusted model included base model plus BMI, diagnosis of AMI, history of hypertension, history of dyslipidemia, history of myocardial infarction, history of arrhythmia, SBP, LVEF, eGFR, hs-CRP, LDL-C, smoking status, and in-hospital treatments (PCI, antiplatelet therapy, β-blocker, ACEI or ARB, and statins)
NT-proBNP, N-terminal pro-B-type natriuretic peptide; MACCEs, major adverse cardio-cerebral events; CI, confidence interval; TyG, triglyceride-glucose; BMI, body mass index; AMI, acute myocardial infarction; SBP, systolic blood pressure; LVEF, left ventricular ejection fraction; eGFR, estimated glomerular filtration rate; hs-CRP, high sensitivity C-reactive protein; LDL-C, low-density lipoprotein cholesterol; PCI, percutaneous coronary intervention; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker