Table 4.

RECIST 1.1. responses in patients evaluable for clinical activity

Response	0.5 mg/kg (N = 2)	1 mg/kg (N = 3)	2 mg/kg (N = 3)	3 mg/kg (N = 3)	5 mg/kg (N = 5)	Total (N = 16)
Response
CR	0	0	0	0	0	0
PR	0	0	0	0	1 (20%)	1 (6.3%)
SD	1 (50.0%)	2 (66.7%)	2 (66.7%)	2 (66.7%)	1 (20%)	8 (50.0%)
PD	1 (50.0%)	1 (33.3%)	1 (33.3%)	1 (33.3%)	3 (60%)	7 (43.8%)

Percentages are based on the number of subjects within each cohort

CR = Complete response, PR = Partial response, SD = Stable disease, PD = Progressive disease