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. Author manuscript; available in PMC: 2023 Sep 13.
Published in final edited form as: Nat Med. 2023 Mar 13;29(3):719–728. doi: 10.1038/s41591-023-02235-5

Extended Data Fig.3. Multivariable-adjusted spline analysis of dietary pattern scores with risk of major chronic disease.

Extended Data Fig.3

P values for nonlinearity based on the two-sided tests were statistically significant for AMED (P = 0.03), WCRF/AICR (P = 0.007), and rEDIP (P = 0.008) (not adjusted for multiple comparisons). The hazard ratios (black line) and the 95% confidence intervals (grey bands) are shown. The models were adjusted for the same list of covariates as in Table 2. AHEI-2010, Alternative Healthy Eating Index-2010; AMED, Alternate Mediterranean Diet score; DASH, Dietary Approaches to Stop Hypertension score; DRRD, Diabetes Risk Reduction Diet; hPDI, Healthful plant-based diet index; HR, Hazard ratio; rEDIH, reversed Empirical dietary index for hyperinsulinemia; rEDIP, reversed Empirical dietary inflammation pattern; WCRF/AICR, World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) dietary score.