Extended Data Table 6.
Associations between cumulative average dietary patterns and risk of major chronic disease using the same reference group
| Pattern | Model | Reference group | Highest Quintile |
|---|---|---|---|
| AHEI-2010 | Cases | 23,708 | 7,660 |
| Person-year | 2,292,086 | 967,242 | |
| Age | 1 | 0.66 (0.64, 0.68) | |
| MV | 1 | 0.75 (0.73, 0.77) | |
| AMED | Cases | 23,708 | 7,625 |
| Person-year | 2,292,086 | 972,409 | |
| Age | 1 | 0.67 (0.65, 0.68) | |
| MV | 1 | 0.77 (0.75, 0.79) | |
| hPDI | Cases | 23,708 | 8,063 |
| Person-year | 2,292,086 | 972,078 | |
| Age | 1 | 0.69 (0.67, 0.71) | |
| MV | 1 | 0.78 (0.76, 0.80) | |
| DASH | Cases | 23,708 | 7,857 |
| Person-year | 2,292,086 | 972,141 | |
| Age | 1 | 0.66 (0.65, 0.68) | |
| MV | 1 | 0.78 (0.76, 0.80) | |
| DRRD | Cases | 23,708 | 7,463 |
| Person-year | 2,292,086 | 972,819 | |
| Age | 1 | 0.64 (0.63, 0.66) | |
| MV | 1 | 0.74 (0.72, 0.76) | |
| WCRF/AICR | Cases | 23,708 | 8,841 |
| Person-year | 2,292,086 | 970,161 | |
| Age | 1 | 0.75 (0.73, 0.77) | |
| MV | 1 | 0.86 (0.84, 0.88) | |
| rEDIH | Cases | 23,708 | 7,164 |
| Person-year | 2,292,086 | 969,987 | |
| Age | 1 | 0.62 (0.60, 0.63) | |
| MV | 1 | 0.67 (0.65, 0.69) | |
| rEDIP | Cases | 23,708 | 6,690 |
| Person-year | 2,292,086 | 971,184 | |
| Age | 1 | 0.64 (0.62, 0.66) | |
| MV | 1 | 0.67 (0.65, 0.69) |
AHEI-2010, Alternative Healthy Eating Index-2010; AMED, Alternate Mediterranean Diet score; CI, Confidence interval; DASH, Dietary Approaches to Stop Hypertension score; DRRD, Diabetes Risk Reduction Diet; hPDI, Healthful plant-based diet index; HR, Hazard ratio; MV, multivariable; rEDIH, reversed Empirical dietary index for hyperinsulinemia; rEDIP, reversed Empirical dietary inflammation pattern; WCRF/AICR, World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) dietary score.
Participants who were in the highest quintile of each dietary pattern were compared with those who were never in the highest quintile of any pattern. Analyses were stratified by age (in month), calendar year, and cohort. MV model: adjusted for family history of diabetes (yes or no), family history of cancer (yes or no), family history of cardiovascular disease (yes or no), physical activity (<3.0, 3.0-8.9, 9.0-17.9, 18.0-26.9, 27.0-41.9, or ≥42 MET-h/week), cigarette smoking status (never, former quitting ≥10 y, former quitting <10 y, current), cigarette smoking pack-years (0, 1-4, 5-14, 15-24, or ≥25 pack-years), multivitamin use (yes or no), regular aspirin use (yes or no), regular non-steroidal anti-inflammatory drugs use (yes or no), postmenopausal hormone use (premenopausal, never, former, or current use) for women, and total energy intake (quintiles). For DASH, hPDI, and DRRD, alcohol consumption (<5.0, 5.0-14.9, or ≥15.0 g/d) was additionally adjusted for.