Table 3.
Summary of relative postmortem decomposition rates of different structural features of cell membranes in the brain.
| Feature | Key points of decomposition patterns |
|---|---|
| Brain region differences | The cerebellum can have faster decomposition than other regions |
| Cell type differences | Smaller cells may decompose faster than larger cells |
| Cell volume | Cell volumes changes are rapid and occur within minutes. Ongoing swelling, shrinkage, and compression processes evolve throughout the PMI |
| Dendrite | Segmental swelling within hours. Highly sensitive to visualization method, and appear to be more stable with more robust methods of visualization |
| Axon | Segmental swelling and volume changes, similar to dendrites |
| Synapse | Morphometric changes, including postsynaptic membrane thickening and changes in curvature, occur within minutes. Variability based on visualization method, but their overall presence is relatively stable in the early PMI |
| Myelin | Lamellar separation without a break in continuity of the separated lamellae. Relatively slow decomposition overall |