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Table 3.

Summary of relative postmortem decomposition rates of different structural features of cell membranes in the brain.

Feature Key points of decomposition patterns
Brain region differences The cerebellum can have faster decomposition than other regions
Cell type differences Smaller cells may decompose faster than larger cells
Cell volume Cell volumes changes are rapid and occur within minutes. Ongoing swelling, shrinkage, and compression processes evolve throughout the PMI
Dendrite Segmental swelling within hours. Highly sensitive to visualization method, and appear to be more stable with more robust methods of visualization
Axon Segmental swelling and volume changes, similar to dendrites
Synapse Morphometric changes, including postsynaptic membrane thickening and changes in curvature, occur within minutes. Variability based on visualization method, but their overall presence is relatively stable in the early PMI
Myelin Lamellar separation without a break in continuity of the separated lamellae. Relatively slow decomposition overall