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. 2023 Apr 17;14(3):e00447-23. doi: 10.1128/mbio.00447-23

FIG 4.

FIG 4

The neutralization of IL-17A alleviated the oral tumor progression promoted by C. albicans infection. (A) Schematic figure of IL-17A neutralization experiment in C3H/HeN-SCC VII mice; CON (C3H/HeN-SCC VII), anti-IL-17A (C3H/HeN-SCC VII with IL-17A neutralization), CA (C3H/HeN-SCC VII with C. albicans infection), and CA + anti-IL-17A (C3H/HeN-SCC VII with C. albicans infection and IL-17A neutralization). (B) Tumor volume. (C) Representative tumor images and H&E images. (D) Representative IF images of IL-17RA (green) and CCL2 (red); scale bar = 75 μm or 25 μm. (E) FCM results of CD11b+F4/80+ macrophages. (F) Representative IF images of F4/80 (green), CD86 (indigo blue), and CD163 (red); scale bar = 100 μm or 50 μm. (G) Representative IF images of F4/80 (green), PD-L1 (indigo blue), and GAL-9 (red); scale bar = 100 μm or 50 μm.