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Non-inferiority immunogenicity in susceptible subjects.
| group | 5-dose PVRV-WIBP vs 5-dose PVRV-LNCD | p-value | 4-dose PVRV-WIBP vs 5-dose PVRV-LNCD | p-value |
|---|---|---|---|---|
| GMT ratio (95%) 0:14:42/35 | 1.21 (1.06,1.37) | .0011 | 1.03 (0.91,1.17) | .5452 |
| GMT ratio (95%) 14 day PWVa | 1.31 (1.17,1.46) | <.0001 | 1.08 (0.98,1.19) | .0892 |
| Seroconversion rate difference (95%) | 0.00 (−1.47,1.45) | 1.0000 | 0.00 (−1.38,1.45) | 1.0000 |
a14-day PWV, 14 days after the whole vaccine schedule. GMT,geometric mean titer.
