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. 2023 May 27;12(6):776. doi: 10.3390/biology12060776

Figure 1.

Figure 1

NF-κB family members. Different subunits belonging to the NF-κB family are shown in the figure in relation to the different functional domains. A Rel Homology Domain (RHD), located at the N-terminal region, is common to all members. RelB is the only subunit containing a leucine zipper domain (LZ). A transactivation domain (TAD), at C-terminal, is only present in p65(RelA), RelB, and c-Rel; whereas p52/p100 and p50/p105 share a glycine rich region (GR), ankyrin repeats, and a death domain (DD).