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Main studies evaluating the antioxidant effects of apixaban. ICAM-1: intercellular adhesion molecule 1; VCAM-1: vascular cell adhesion protein 1; ROS: reactive oxygen species; NOS: nitric oxide synthase; HUVECs: human umbilical vein endothelial cells; HMEC-1: human mammary epithelial cells.
| Authors | Protocol | Patients | Target | Dose | Results |
|---|---|---|---|---|---|
| Torramade-Moix [173] | Preclinical in vitro | - | HUVECs and HMEC-1 | - | ↓ ICAM-1 ↓ VCAM-1 ↓ ROS ↑ NOS |
