Drug-induced changes in the expression of genes related to neuroreceptors, HPA axis hormones, and synapses/synaptogenesis in the cochleae of 7-month-old Fus1 KO mice. (A–C) These plots illustrate the percentage change in the expression of genes related to (A) neuroreceptors, (B) hormones of the hypothalamus–pituitary–adrenal (HPA) axis, and (C) synapses and regulators of synaptogenesis in the cochleae of untreated control and drug-treated Fus1 KO mice relative to WT mice. The plots on the right of the axis represent upregulated genes, while the plots on the left of the axis represent downregulated genes.