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Drug-specific correction of critical biological processes dysregulated in the Fus1 KO mouse cochlea. This schematic illustrates biological processes that were upregulated or downregulated in the cochleae of 7-month-old Fus1 KO mice in response to rapamycin (RAPA) and 2-deoxy-D-glucose (2-DG) treatment. ⬆= upregulation, ⬇= downregulation.
| RAPA | 2-DG |
|---|---|
| Calcium signaling ⬆ | Metabolism ⬇ Immune system ⬆ |
| Immune system ⬆ | |
| Signaling transduction ⬆ | |
| Cell adhesion ⬆ |
