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. 2023 Jun 20;13(12):2045. doi: 10.3390/ani13122045

Table 3.

Summary of the different studies on oral gabapentin use in horses.

Medical Condition Therapeutic Regimen Clinical Endpoint Outcome Study Type Reference
Neuropathic pain following colic surgery An amount of 2.5 mg/kg every 8 h for six days Managing chronic neuropathic pain Beneficial Case report (n = 1) [45]
Healthy An amount of 20 mg/kg, single dose To assess cardiovascular, sedative and behavioral effects Nonbeneficial Randomized, cross-over trial
(n = 6)
[92]
Temporohyoid osteoarthropathy An amount of 5 mg/kg every 12 h for 10 weeks as adjunctive therapy Reducing the violent head shaking Beneficial Case report (n = 1) [44]
Chronic lameness An amount of 5–10 mg/kg every 8 h for 14 days Managing chronic pain Nonbeneficial Randomized, cross-over, placebo-controlled, double-blinded trial (n = 6) [91]
Chronic lameness An amount of 20 mg/kg every 12 h for 6.5 days Managing chronic pain Potentially beneficial if associated with firocoxib (57 mg/day) Randomized, cross-over, placebo-controlled, masked trial (n = 14) [43]