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. 2023 May 22;5(13):3463–3484. doi: 10.1039/d3na00157a

Comparison of the obtained results for the HCR using the catalyst 1 and other catalytic systems.

Entry Catalyst Reaction conditions Catalyst amount Time (h) Yield (%) Reference
1 Trifunctional N,N,O-terdentate amido/pyridyl carboxylate DMF/145 °C/Na2CO3 0.01 mol% 20 92 140
Pd(ii) complexes
2 Pd(OAc)2 NMP/135 °C/NaOAc/UV-VIS 0.05 mol% 44 80 141
3 CMH–Pd(0) DMF/120 °C/Et3N 50 mg 6 90 142
4 NHC–Pd/IL@SiO2 NMP/140 °C/NaOAc 0.01 mol% 24 94 143
5 Pd(quinoline-8-carboxylate)2 DMF/130 °C/K2CO3 0.01 mol% 30 39–94 144
6 OCMCS–Pd DMF/140 °C/Et3N 0.02 mmol 12 89–98 145
7 Pd@MET-EDTA-CS DMF/90 °C/K 2 CO 3 0.0027 mol% 16 95 This work
8 Pd@MET-EDTA-CS CH 3 CN/80 °C/K 2 CO 3 0.0027 mol% 18 95 This work