Figure 1.

Transmural histotopograms of left ventricular (LV) tissue from rat hearts. (a)—the tissue samples from control group 1; (b)—the tissue samples from rats after AX administration, group 2; (c)—the tissue samples from rats with ISO injection, group 3; (d) the tissue samples from rats after AX administration and injected with ISO, group 4. Main images reflect Masson’s trichrome stain (collagen/fibrosis—blue, muscles and other tissues—red, cell nuclei—brown), ruler 500 μm. Upper inserts—enlarged fragments of the subendocardial zone of the myocardium with predominantly cross sections of myocardial fibers; Lilly’s trichrome stain (collagen/fibrosis shown in blue, muscles and other tissues in red-brown, cell nuclei in brown-black), ruler 100 μm. Lower inserts—enlarged fragments of the middle zone of the myocardium; H&E (cell nuclei in blue, erythrocytes in red, muscle tissue in pink); ruler 100 μm.