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. 2023 Jun 7;10(6):695. doi: 10.3390/bioengineering10060695

Table 2.

Clinical parameters (mean ± SD) for target sites in early and late orthodontic treatment (OT) group at baseline, 12 months and 24 months. Differences between follow-up visits in CAL or PPD after 24 months (secondary outcome) were tested by paired t-test.

Variable Early OT (n = 23) Late OT (n = 20)
Baseline 12 mo 24 mo BL vs. 24 mo Baseline 12 mo 24 mo BL vs. 24 mo
CAL (mean ± SD) mm 9.8 ± 2.5 4.4 ± 1.7 3.9 ±1.9 p <0.0001 9.2 ± 2.5 4.7 ± 2.4 4.50 ± 2.19 p < 0.0001
Estimate 95% CI [8.8, 10.9] [3.7, 5.2] [3.1, 4.7] [5.0, 6.7] [8.0, 10.4] [3.6, 5.8] [3.5, 5.5] [3.9, 5.5]
PPD (mean ± SD) mm 7.3 ± 1.6 3.1 ± 0.9 2.9 ± 0.9 p < 0.0001 7.1 ± 1.7 3.2 ± 1.1 3.2 ± 0.9 p < 0.0001
Estimate 95% CI [6.6, 8.0] [2.7, 3.5] [2.5, 3.3] [3.7, 5.1] [6.3, 7.9] [2.7, 3.7] [2.7, 3.6] [3.1, 5.4]
PI n (%) 4 (17%) 3 (13%) 2 (8%) 1 (5%) 2 (10%) 2 (10%)
BOP n (%) 13 (53%) 7 (30%) 4 (17%) 9 (45%) 3 (15%) 0 (0%)
PUS n (%) 1 0 0 2 0 0
Pocket closure (PPD ≤ 4 mm) n (%) n/a 21 (91%) 21 (91%) n/a 17 (85%) 18 (90%)
Pocket closure (PPD ≤ 4 mm, no BOP) n (%) n/a 16 (69%) 18 (78%) n/a 15 (75%) 15 (75%)

BL: Baseline, CAL: Clinical Attachment Level, PPD: Probing Pocket Depth, PI: Plaque Index, BOP: Bleeding on Probing, PUS: Suppuration, CI: Confidence Interval.