FIGURE 2:

CRISPR/Cas9 KO cell lines exhibit different patterns of albumin binding and uptake. Control, Cubn KO, Lrp2 KO, and Dab2 KO cells were incubated with 50 µg/ml AlexaFluor-647 albumin for 15 min at 37°C and then fixed and visualized by confocal microscopy. Representative xz sections are shown below each panel. Scale bar: 10 µm.