Table 2.

Risk of bias assessment tool according to Mikolajewicz et al. [50,51].

Author and Year	Peer- Reviewed	Complete stat	Randomization	Blindness	Sample Size Calculation	Dose-Response Relation	Statement of Compliance with Regulatory	Objective Aligned with Analysis	Risk of Bias
Sadek et al., 2023 [52]	+	+	-	-	+	+	+	+	Low
Bergamo et al., 2022 [53]	+	+	+	-	-	+	+	+	Low
Britto et al., 2022 [54]	+	+	+	-	-	+	+	+	Low
de Castro et al., 2022 [55]	+	+	+	-	-	+	+	+	Low
Ellakany et al., 2022 [56]	+	+	+	-	+	+	+	+	Low
Pantea et al., 2022 [57]	+	+	+	-	-	+	+	+	Low
Simoneti et al., 2022 [58]	+	+	+	-	-	+	+	+	Low
Tasin et al., 2022 [59]	+	+	-	-	+	+	+	+	Low
Turksayar et al., 2022 [60]	+	+	-	-	+	+	+	+	Low
Al-Qahtani et al., 2021 [61]	+	+	-	-	-	-	+	+	Moderate
Mayer et al., 2021 [62]	+	+	-	-	-	+	+	+	Moderate
Myagmar et al., 2021 [63]	+	+	+	-	-	+	+	+	Low
Martín-Ortega et al., 2021 [64]	+	+	+	-	-	+	+	+	Low
Park et al., 2020 [65]	+	+	-	-	-	+	-	+	Moderate
Reeponmaha et al., 2020 [66]	+	+	+	-	+	+	+	+	Low
Kessler et al., 2019 [67]	+	+	-	-	-	+	+	+	Low
Park et al., 2018 [68]	+	+	-	-	-	+	+	+	Moderate
Tahayeri et al., 2018 [69]	+	+	-	-	-	+	+	+	Low
Digholkar el al, 2016 [70]	+	+	-	-	-	+	+	+	Moderate

+: positive assessment of the item; -: negative assessment of the item.