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. 2023 May 30;11(6):1592. doi: 10.3390/biomedicines11061592

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of oxygen delivery on in vivo tissue regeneration of implanted scaffolds. (A) Elevated skin wound healing in the presence of PUAO and CPO-loaded PUAO as compared to control and bare PU groups. (B) Effect of oxygen-generating microparticles (OGMs) on the regeneration of critical-sized bone defects: (a,d,g) control group with minimal bone formation, (b,e,h) pristine hydrogel with a little regeneration, (c,f,i) OGM-mediated elevated bone regeneration by week 12. The figures were adopted from ref [21,48] with permission from Elsevier, Limited.