Figure 4.
Positional isomeric N-glycans that show significant differences in CRC. Four positional isomers with significant differences were observed, as denoted by each row. (A1–D1) Boxplots of relative abundances observed in pre- (n = 64) and post-operative (n = 64) samples for each isomeric form. (A2–D2) Fold-change in CRC (pre-/post-, n = 64) for each isomer whereby an increase (>1) or a decrease (<1) may be observed. Asterisks denote significance with p-value < 0.05 (*), 0.01 (**), 0.001 (***), 0.0001 (****). Abbreviations: Not significant (ns), hexose (H), N-acetylhexosamine (N), fucose (F), amidated α2,3-linked N-acetylneuraminic acid (Am), and ethyl esterified α2,6-linked N-acetylneuraminic acid (E).
