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. 2023 May 28;11(6):1567. doi: 10.3390/biomedicines11061567

Figure 4.

Figure 4

Summary: The basis of the described changes has its origin in genes and epigenetics. Immunological and metabolic disorders trigger an unfavorable hormonal profile. These dependencies interpenetrate and trigger each other and lead to a clinical picture of PCOS and infertility. This has been shown by red arrows, which most likely indicate the main pathways of the pathomechanism of PCOS and infertility.