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. 2023 May 7;10(6):ofad244. doi: 10.1093/ofid/ofad244

Table 2.

Characteristics of Laboratory-Confirmed Influenza Cases, Stratified by Age Group

Feature, N (%) <5 Years 5–17 Years 18–49 Years 50–64 Years 65–79 Years 80+ Years P for Temporal Trend
N 1149 (32.7) 359 (10.2) 769 (21.9) 456 (13.0) 504 (14.4) 275 (7.8)
Male sex 516 (44.9) 153 (42.6) 477 (62.0) 233 (51.1) 236 (46.8) 156 (56.7) .452
Smoking Habit
 Current smoker (parent smoking status for children) 348 (30.3) 101 (28.1) 186 (24.2) 149 (32.7) 105 (20.8) 20 (7.3) .132
 Never smoker 635 (55.3) 212 (59.1) 499 (64.9) 180 (39.5) 201 (39.9) 160 (58.2) 1.000
 Past smoker 121 (10.5) 40 (11.1) 84 (10.9) 127 (27.9) 198 (39.3) 95 (34.5) 1.000
 Not available 45 (3.9) 6 (1.7) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Influenza Vaccination in the Current Season 39 (3.4) 18 (5.0) 33 (4.3) 37 (8.1) 99 (19.6) 97 (35.3) .024
 Not available 31 (2.7) 5 (1.4) 23 (3.0) 31 (6.8) 37 (7.3) 26 (9.5)
Presenting Symptoms
 Fever 0 (0.0) 355 (98.9) 743 (96.6) 431 (94.5) 455 (90.3) 222 (80.7) .027
  Not available 1149 (100) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
 Cough 0 (0.0) 341 (95.0) 695 (90.4) 425 (93.2) 441 (87.5) 235 (85.5) 0.086
  Not available 1149 (100) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
 Shortness of breath 0 (0.0) 75 (20.9) 267 (34.7) 265 (58.1) 311 (61.7) 207 (75.3) 0.027
  Not available 1149 (100) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
 Malaise 0 (0.0) 282 (78.6) 574 (74.6) 327 (71.7) 323 (64.1) 186 (67.6) 0.086
  Not available 1149 (100) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
 Headache 0 (0.0) 158 (44.0) 470 (61.1) 222 (48.7) 213 (42.3) 75 (27.3) .220
  Not available 1149 (100) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
 Myalgias 0 (0.0) 120 (33.4) 384 (49.9) 236 (51.8) 230 (45.6) 111 (40.4) 1.000
  Not available 1149 (100) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
 Sore throat 0 (0.0) 175 (48.7) 372 (48.4) 184 (40.4) 167 (33.1) 65 (23.6) .027
  Not available 1149 (100) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Chronic Comorbidities
 Any chronic comorbidities 124 (10.8) 58 (16.2) 283 (36.8) 352 (77.2) 460 (91.3) 261 (94.9) .008
  Not available 1 (0.1) 0 (0) 0 (0) 0 (0) 1 (0.2) 0 (0)
 Cardiovascular disease/high blood pressure 17 (1.5) 6 (1.7) 55 (7.2) 185 (40.6) 318 (63.1) 190 (69.1) .024
Not Available 183 (15.9) 15 (4.2) 4 (0.5) 6 (1.3) 9 (1.8) 4 (1.5)
 Chronic obstructive pulmonary disease 13 (1.1) 5 (1.4) 21 (2.7) 81 (17.8) 149 (29.6) 78 (28.4) 0.024
  Not available 35 (3.0) 4 (1.1) 4 (0.5) 6 (1.3) 9 (1.8) 4 (1.5)
 Asthma 9 (0.8) 17 (4.7) 42 (5.5) 28 (6.1) 35 (6.9) 26 (9.5) .008
  Not available 183 (15.9) 15 (4.2) 4 (0.5) 6 (1.3) 9 (1.8) 4 (1.5)
 Diabetes mellitus 1 (0.1) 0 (0.0) 44 (5.7) 103 (22.6) 153 (30.4) 74 (26.9) .060
  Not available 35 (3.0) 4 (1.1) 4 (0.5) 6 (1.3) 9 (1.8) 4 (1.5)
 Immunodeficiency (except HIV)/organ transplant 7 (0.6) 2 (0.6) 27 (3.5) 17 (3.7) 19 (3.8) 6 (2.2) .259
  Not available 35 (3.0) 4 (1.1) 4 (0.5) 6 (1.3) 9 (1.8) 4 (1.5)
 Renal impairment 1 (0.1) 0 (0.0) 19 (2.5) 37 (8.1) 53 (10.5) 44 (16.0) .024
  Not available 35 (3.0) 4 (1.1) 4 (0.5) 6 (1.3) 9 (1.8) 4 (1.5)
 Rheumatologic disease/autoimmune disease 0 (0.0) 1 (0.3) 18 (2.3) 18 (3.9) 27 (5.4) 24 (8.7) .008
  Not available 35 (3.0) 4 (1.1) 4 (0.5) 6 (1.3) 9 (1.8) 4 (1.5)
 Neurological or neuromuscular disease 9 (0.8) 8 (2.2) 14 (1.8) 20 (4.4) 37 (7.3) 39 (14.2) .024
  Not available 35 (3.0) 4 (1.1) 4 (0.5) 6 (1.3) 9 (1.8) 4 (1.5)
 Cirrhosis/liver disease 2 (0.2) 2 (0.6) 14 (1.8) 20 (4.4) 19 (3.8) 6 (2.2) .132
  Not available 35 (3.0) 4 (1.1) 4 (0.5) 6 (1.3) 9 (1.8) 4 (1.5)
 Neoplasm 1 (0.1) 8 (2.2) 24 (3.1) 42 (9.2) 66 (13.1) 29 (10.5) .024
  Not available 35 (3.0) 4 (1.1) 4 (0.5) 6 (1.3) 9 (1.8) 4 (1.5)
 Obesity 0 (0.0) 0 (0.0) 52 (6.8) 48 (10.5) 66 (13.1) 49 (17.8) .012
  Not available 35 (3.0) 4 (1.1) 33 (4.3) 29 (6.4) 30 (6.0) 25 (9.1)
 Active tuberculosis 0 (0.0) 0 (0.0) 2 (0.3) 1 (0.2) 0 (0.0) 0 (0.0) 1.000
  Not available 36 (3.1) 6 (1.7) 18 (2.3) 44 (9.6) 104 (20.6) 101 (36.7)
 HIV infection 19 (1.7) 0 (0.0) 13 (1.7) 3 (0.7) 2 (0.4) 0 (0.0) .338
  Not available 36 (3.1) 6 (1.7) 18 (2.3) 44 (9.6) 104 (20.6) 101 (36.7)
Antivirals 339 (29.5) 92 (25.6) 210 (27.3) 127 (27.9) 157 (31.2) 94 (34.2) .132

Abbreviations: HIV, human immunodeficiency virus.