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. 2023 May 7;10(6):ofad244. doi: 10.1093/ofid/ofad244

Table 3.

Influenza (Strain and Subtype) and Multiplex Results by age Group

Virus Strain and Subtypes <5 Years 5–17 Years 18–49 Years 50–64 Years 65–79 Years 80+ Years P for Temporal Trend
N (%) 1149 (32.7) 359 (10.2) 769 (21.9) 456 (13.0) 504 (14.4) 275 (7.8)
Influenza A/H1N1pdm09 663 (57.7) 198 (55.2) 337 (43.8) 242 (53.1) 216 (42.9) 73 (26.5) .024
Influenza A/H3N2 407 (35.4) 121 (33.7) 327 (42.5) 138 (30.3) 189 (37.5) 153 (55.6) .452
Influenza A unsubtyped 85 (7.4) 17 (4.7) 78 (10.1) 73 (16.0) 86 (17.1) 38 (13.8) .132
Influenza B Yamagata 14 (1.2) 8 (2.2) 17 (2.2) 11 (2.4) 11 (2.2) 13 (4.7) .259
Influenza B Victoria 21 (1.8) 6 (1.7) 11 (1.4) 0 (0.0) 4 (0.8) 0 (0.0) .035
Influenza B unsubtyped 28 (2.4) 12 (3.3) 6 (0.8) 0 (0.0) 4 (0.8) 0 (0.0) .180
Multiplex virus-virus codetectionsa
Human seasonal coronavirus type not specified 8 (0.7) 2 (0.6) 3 (0.4) 1 (0.2) 4 (0.8) 0 (0.0) .259
 Not available 119 (10.4) 7 (1.9) 67 (8.7) 34 (7.5) 28 (5.6) 11 (4.0)
Metapneumovirus 13 (1.1) 1 (0.3) 3 (0.4) 3 (0.7) 0 (0.0) 0 (0.0) .180
 Not available 110 (9.6) 14 (3.9) 62 (8.1) 28 (6.1) 22 (4.4) 11 (4.0)
RSV 45 (3.9) 2 (0.6) 2 (0.3) 3 (0.7) 5 (1.0) 3 (1.1) .707
 Not available 94 (8.2) 12 (3.3) 61 (7.9) 28 (6.1) 22 (4.4) 11 (4.0)
Adenovirus 6 (0.5) 2 (0.6) 1 (0.1) 1 (0.2) 0 (0.0) 0 (0.0) .085
 Not available 174 (15.1) 12 (3.3) 67 (8.7) 34 (7.5) 28 (5.6) 11 (4.0)
Bocavirus 3 (0.3) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) .241
 Not available 174 (15.1) 12 (3.3) 67 (8.7) 34 (7.5) 28 (5.6) 11 (4.0)
Parainfluenza type not specified 5 (0.4) 2 (0.6) 0 (0.0) 0 (0.0) 1 (0.2) 0 (0.0) .314
 Not available 175 (15.2) 12 (3.3) 67 (8.7) 34 (7.5) 28 (5.6) 11 (4.0)
Rhinovirus 6 (0.5) 5 (1.4) 4 (0.5) 4 (0.9) 5 (1.0) 1 (0.4) .707
 Not available 190 (16.5) 14 (3.9) 67 (8.7) 34 (7.5) 28 (5.6) 11 (4.0)

Abbreviations: RSV, respiratory syncytial virus.

a

Not all recruiting sites have run multiplex tests. For standardization purposes, the totality of laboratory-confirmed influenza cases was considered the denominator to estimate the proportions per age group.