Table 1.

Recent studies using naltrexone (including LDN and ultra-LDN).

Naltrexone Dosage	Clinical Uses
50–300 mg (regular dose)	Opiate, Alcohol addiction
1–5 mg (LDN)	Fibromyalgia, arthritis, Crohn’s disease, multiple sclerosis
0.001–1 mg very low-dose naltrexone (VLDN)	Reduced side effects and withdrawal symptoms of opiates
<0.001 mg (ULDN)	Similar to VLDN, OA, low back pain, postoperative pain control