Table 6.
The application of multiple criteria in the metabolic pathway analysis.
| Result | Visualization Methods | Enrichment Method | Topology Analysis | Reference Metabolome | Pathway Library |
|---|---|---|---|---|---|
| 1 | Scatter plot | Hypergeometric test | Relative-betweenness centrality R-b C |
All compounds in the selected pathway library | Homo sapiens (KEGG) |
| 2 | Scatter plot | Hypergeometric test | Out-degree Centrality O-d C |
All combinations in the selected pathway library | Homo sapiens (KEGG) |
| 3 | Scatter plot | Hypergeometric test | Relative-betweenness centrality | All compounds in the selected pathway library | Homo sapiens (SMPDB) |
| 4 | Scatter plot | Hypergeometric test | Out-degree Centrality | All combinations in the selected pathway library | Homo sapiens (SMPDB) |