Table 7.
The final results from the metabolic pathway analysis. Further discussion of two items from the KEGG database (nitrogen metabolism, alanine, aspartate, and glutamate metabolism) and three from the SMPDB database (alanine metabolism, aspartate metabolism, and malate-aspartate shuttle) due to vitality. “+”: accept; “--”: reject.
KEGG Database | SMPDB Database | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Result 1 | R-b C Impact |
FDR | Result 2 | O-d C Impact |
FDR | Result 3 | R-b C Impact |
FDR | Result 4 | O-d C Impact |
FDR |
Final Decision (FD) | Final Decision (FD) | Final Decision (FD) | Final Decision (FD) | ||||||||
Nitrogen metabolism | 1 | 0.043213 | Arginine biosynthesis | 0.8125 | 1.90 × 10−7 | Alanine metabolism | 1 | 0.010641 | Malate-aspartate shuttle | 0.63333 | 0.013128 |
FD: + | FD: -- | FD: + | FD: + | ||||||||
Phenylalanine, tyrosine, and tryptophan biosynthesis | 1 | 0.12885 | Alanine, aspartate, and glutamate metabolism | 0.75 | 1.73 × 10−7 | Trehalose degradation | 0.84211 | 0.18355 | Phosphatidylcholine biosynthesis | 0.56707 | 0.00011577 |
FD: -- | FD: + | FD: -- | FD: -- | ||||||||
Synthesis and degradation of ketone bodies | 0.86667 | 0.18716 | Valine, leucine, and isoleucine biosynthesis | 0.75 | 8.82 × 10−5 | Aspartate metabolism | 0.8 | 0.0044894 | Transfer of acetyl groups into mitochondria | 0.54167 | 0.010641 |
FD: -- | FD: -- | FD: + | FD: -- | ||||||||
Alanine, aspartate, and glutamate metabolism | 0.81732 | 1.73 × 10−7 | Nitrogen metabolism | 0.75 | 0.043213 | Glycerol phosphate shuttle | 0.7619 | 0.3023 | Ammonia recycling | 0.49306 | 0.00011577 |
FD: + | FD: + | FD: -- | FD: -- | ||||||||
One-carbon pool by folate | 0.80793 | 0.46957 | Phenylalanine, tyrosine, and tryptophan biosynthesis | 0.75 | 0.12885 | Malate-Aspartate Shuttle | 0.71429 | 0.013128 | Cardiolipin biosynthesis | 0.49057 | 0.013128 |
FD: -- | FD: -- | FD: + | FD: -- |