AA	Arachidonic acid
2-AG	2-Arachidonoylglycerol
AC	Adenylate cyclase
AEA	Anandamide
ALT	Alanine aminotransferase
ATM	Adipose tissue macrophage
BBB	Blood–brain barrier
BMI	Body mass index
cAMP	Cyclic adenosine monophosphate
CB1R	Cannabinoid-receptor type 1
CB2R	Cannabinoid-receptor type 2
CBD	Cannabidiol
CBR	Cannabinoid receptor
CNS	Central nervous system
CRP	C-reactive protein
DA	Dopamine
DALY	Disability-adjusted life-years
DM	Diabetes mellitus
DN	Diabetic nephropathy
DPN	Diabetic peripheral neuropathy
DRP	Diabetic retinopathy
EAE	Experimental autoimmune encephalomyelitis
ECB	Endocannabinoid
ECS	Endocannabinoid system
ERK	Extracellular signal-regulated kinase
FAAH	Fatty acid amide hydrolase
FDA	Food and Drug Administration
FR	Fixed-ratio
GLUT 4	Glucose transporter type 4
GPCR	G-protein-coupled receptor
GSIS	Glucose-stimulated insulin secretion
HbA1C	Glycated hemoglobin
HDL	High-density lipoprotein
HOMA-IR	Homeostasis model assessment of insulin resistance
IDF	International Diabetes Federation
IKK-β	Inhibitor of nuclear factor kappa-B kinase subunit β
iNOS	Inducible NO synthase
IRF5	Interferon regulatory factor-5
JNK	c-Jun N-terminal kinase
MAPK	Mitogen-activated protein kinase
MEK	Mitogen-activated protein kinase kinase
MNU	N-Methyl-N-nitrosurea
NAc	Nucleus accumbens
nAChR	Nicotinic acetylcholine receptor
NCD	Non-communicable disease
NK	Natural killer
NLRP3	Nucleotide-binding domain and leucine-rich repeat protein 3
NSAID	Non-steroidal anti-inflammatory drug
PI3K	Phosphatidylinositol 3-kinase
PPAR	Peroxisome proliferator-activated receptor
PR	Progressive ratio
PUFA	Polyunsaturated fatty acid
R	Receptor
ROS	Reactive oxygen species
SC	Synthetic cannabinoid
sP	Sardinian alcohol-preferring
STRATUS	Studies with Rimonabant and Tobacco Use
STZ	Streptozotocin
T1DM	Type 1 diabetes mellitus
T2DM	Type 2 diabetes mellitus
TNF-α	Tumor necrosis factor-α
TRPA1	Transient receptor potential ankyrin 1
TRPV1	Transient receptor potential vanilloid 1
US	United States
VTA	Ventral tegmental area
WHO	World Health Organization
ZDF	Zucker diabetic fatty
γ-GT	Gamma-glutamyl transferase
∆8-THCV	∆8-Tetrahydrocannabivarin
Δ9-THC	Δ9-Tetrahydrocannabinol
AA	Arachidonic acid