Table 1.
Selected somatic mtDNA mutation frequencies in cancers.
| Cancer | Somatic Mutation Frequency (%) |
|---|---|
| Skin | 16–75 |
| Head and neck | 49–78 |
| Thyroid | 23–100 |
| Breast | 30–93 |
| Lung | 43–79 |
| Esophageal | 5–55 |
| Gastric | 18–81 |
| Colorectal | 16–70 |
| Pancreatic | 16–92 |
| Liver | 40–68 |
| Renal | 27–79 |
| Urinary Bladder | 64–100 |
| Prostate | 19–88 |
| Ovarian | 20–80 |
| Endometrial | 9–63 |
| Cervical | 38–90 |
| Nervous system | <35 |
| Hematological | 30–50 |
| Connective tissue | <70 |
Summary of selected somatic mtDNA mutation frequencies across numerous cancers.