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. 2023 Jun 6;15(12):3069. doi: 10.3390/cancers15123069

Table 4.

Sensitivity per prognostic subgroup for screen-detected and interval cancers combined.

Variable N Detected AI SEN AI 95% CI Detected R1 SEN R1 95% CI p
Invasive Component not present 341 264 77.4% 72.9–81.8% 294 86.2% 82.5–89.9% <0.001
present 1607 1278 79.5% 77.6–81.5% 1276 79.4% 77.4–81.4% 0.954
missing 63
Tumour grade grade 1 401 329 82.0% 78.3–85.6% 332 82.8% 78.9–86.5% 0.836
grade 2 845 676 80.0% 77.2–82.6% 680 80.5% 77.7–83.0% 0.805
grade 3 307 223 72.6% 67.6–77.5% 215 70.0% 64.9–75.3% 0.322
missing 54
Whole tumour size ≤20 mm 911 742 81.4% 78.9–83.9% 745 81.8% 79.2–84.2% 0.880
>20 mm 492 381 77.4% 73.7–81.1% 385 78.3% 74.6–81.9% 0.752
missing 204
Invasive tumour size ≤20 mm 1168 941 80.6% 78.3–82.7% 950 81.3% 79.1–83.5% 0.594
>20 mm 289 210 72.7% 67.5–77.8% 197 68.2% 62.8–73.5% 0.092
missing 150
Lymph node status negative 1110 906 81.6% 79.3–83.8% 918 82.7% 80.4–84.9% 0.460
positive 298 235 78.9% 74.2–83.6% 234 78.5% 73.7–83.1% 0.999
missing 199

Abbreviations: AI—artificial intelligence; R1—human reader 1; CI—confidence interval. Tumour grade, whole tumour size, invasive tumour size, and lymph node status were only assessed for cancers that had an invasive component present. p values are based on McNemar’s test.