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. 2023 Jun 19;13(6):1013. doi: 10.3390/biom13061013

Figure 3.

Figure 3

Effect of 5-HT on load-free cell shortening. (A–C) Concentration–response curves for myocytes from MAO-B expressing mice myocytes (MAO-B+/+, n = 54–72), MAO-B knockout myocytes (MAO-B−/−, n = 65–72), and ARVM (n = 28–45). Cells were exposed to 5-HT for 24 h and cell shortening was subsequently analyzed as in Figure 1. (D) Effect of clorgyline (Clorg, 1 µM), 5-HT (100 µM), and combinations thereof (n = 45–108). Data are full ranges (whiskers) with median and 25 and 75% quartiles (boxes). *; p < 0.05 vs. control; Kruskal–Wallis test with Bonferroni (correction for multiple testing) post hoc analysis.