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. 2023 Jun 7;12(12):1573. doi: 10.3390/cells12121573

Figure 1.

Figure 1

(a) Blood is the most commonly used body fluid for liquid biopsies. The most studied liquid biopsy biomarkers are depicted, namely circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), cell-free RNA (cfRNA), extracellular vesicles (EVs) and tumor-educated platelets (TEPs). Cell-free DNA (cfDNA) is also shown. (b) ctDNA carries the same genomic (point mutations, insertions/deletions, translocations, copy number variations) and epigenomic (DNA methylation) alterations as the tissue tumor DNA. This image was created with the use of BioRender (https://biorender.com/) (accessed on 20 April 2023).