Table 2.
Top ten up- and downregulated differentially expressed genes from a total of 355 DEGs in breast cancer.
| Gene Symbol | Gene Name | Log2FC | adj.p-Value | Decide Test |
|---|---|---|---|---|
| COL11A1 | Collagen Type XI Alpha 1 Chain | 4.36 | 1.69 × 10−172 | Upregulated |
| TOP2A | DNA Topoisomerase II Alpha | 3.96 | 4.16 × 10−220 | Upregulated |
| S100P | S100 Calcium-Binding Protein P | 3.70 | 3.57 × 10−137 | Upregulated |
| COL10A1 | Collagen Type X Alpha 1 Chain | 3.59 | 7.47 × 10−192 | Upregulated |
| RRM2 | Ribonucleotide Reductase Regulatory Subunit M2 | 3.47 | 4.44 × 10−205 | Upregulated |
| CKS2 | CDC28 Protein Kinase Regulatory Subunit 2 | 3.26 | 8.66 × 10−201 | Upregulated |
| MMP1 | Matrix Metallopeptidase 1 | 3.21 | 7.95 × 10−113 | Upregulated |
| COMP | Cartilage Oligomeric Matrix Protein | 3.15 | 6.27 × 10−137 | Upregulated |
| NUSAP1 | Nucleolar And Spindle-Associated Protein 1 | 3.08 | 9.67 × 10−194 | Upregulated |
| ANLN | Anillin, Actin-Binding Protein | 3.07 | 2.42 × 10−173 | Upregulated |
| ADH1B | Alcohol Dehydrogenase 1B (Class I), Beta Polypeptide | −4.84 | 2.10 × 10−168 | Downregulated |
| ADIPOQ | Adiponectin, C1Q And Collagen Domain Containing | −4.47 | 6.08 × 10−119 | Downregulated |
| PLIN1 | Perilipin 1 | −4.20 | 8.42 × 10−161 | Downregulated |
| LEP | Leptin | −4.11 | 7.20 × 10−105 | Downregulated |
| LPL | Lipoprotein Lipase | −4.09 | 2.35 × 10−130 | Downregulated |
| SDPR | Serum Deprivation Response | −4.06 | 1.34 × 10−201 | Downregulated |
| RBP4 | Retinol Binding Protein 4, Plasma | −4.06 | 4.37 × 10−118 | Downregulated |
| C2orf40 | Chromosome 2 Open Reading Frame 40 | −4.05 | 3.15 × 10−211 | Downregulated |
| ABCA8 | Atp-Binding Cassette Subfamily A Member 8 | −4.05 | 4.21 × 10−166 | Downregulated |
| NTRK2 | Neurotrophic Tyrosine Kinase, Receptor, Type 2 | −4.04 | 4.78 × 10−181 | Downregulated |