Table 9.
Expression of gene signatures in microarray and qRT-PCR. The results of qRT-PCR are represented by the quantitative expression (Rq) and fold-change (FC), along with the standard deviation (StdDev) and p-values.
| Gene | Microarray | qRT-PCR | ||||
|---|---|---|---|---|---|---|
| FC | adj.p-Value | Rq | FC | StdDev | p-Value | |
| Expression of Diagnostic Gene Signature | ||||||
| COL11A1 | 3.907519 | 5.1 × 10−163 | 9.834254 | 3.297816 | 0.64495 | 3.47 × 10−7 |
| COL10A1 | 3.842333 | 2.1 × 10−178 | 10.30614 | 3.365432 | 0.660567 | 1.84 × 10−8 |
| S100P | 3.701498 | 3.6 × 10−137 | 5.345665 | 2.418369 | 0.995349 | 2.73 × 10−11 |
| COMP | 3.150415 | 6.3 × 10−137 | 6.191366 | 2.630258 | 0.425433 | 5.81 × 10−15 |
| INHBA | 3.042628 | 2.6 × 10−157 | 7.21937 | 2.851873 | 0.901961 | 1.97 × 10−8 |
| WISP1 | 2.551547 | 6 × 10−105 | 4.783692 | 2.258124 | 0.461439 | 2.9 × 10−8 |
| ADAMTS5 | −3.13169 | 3.3 × 10−184 | 0.209914 | −2.25213 | 0.511629 | 2.88 × 10−9 |
| CXCL10 | 2.530934 | 2.16 × 10−95 | 4.763343 | 2.251974 | 0.86944 | 2.16 × 10−5 |
| LYVE1 | −3.14204 | 1.2 × 10−142 | 0.177332 | −2.49548 | 0.877592 | 1.73 × 10−6 |
| Expression of Prognostic Gene Signature | ||||||
| CCNE2 | 2.530327 | 3.7 × 10−154 | 5.112678 | 2.354079 | 0.392123 | 3.1 × 10−15 |
| NUSAP1 | 2.732299 | 2.4 × 10−124 | 7.065653 | 2.820823 | 0.9127 | 3.81 × 10−10 |
| TPX2 | 2.145025 | 5.6 × 10−135 | 5.179436 | 2.372795 | 0.432888 | 4.72 × 10−10 |
| ITM2A | −2.54576 | 9.1 × 10−149 | 0.241341 | −2.05085 | 0.683145 | 4.21 × 10−8 |
| LIFR | −3.0494 | 5.6 × 10−159 | 0.271185 | −1.88265 | 0.853309 | 1.78 × 10−6 |
| TNXA | −2.54523 | 1.9 × 10−129 | 0.228871 | −2.12739 | 0.736176 | 7.89 × 10−7 |
| ZBTB16 | −2.4943 | 1.12 × 10−115 | 0.187856 | −2.4123 | 0.567998 | 3.32 × 10−9 |
| S100P | 3.701498 | 3.6 × 10−137 | 5.345665 | 2.418369 | 0.995349 | 2.73 × 10−11 |