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Kaplan–Meier analysis of PFS and OS according to the percentage of Treg and exhausted CD8+ T cells in patients treated with crizotinib. (A,B) The difference in PFS between patients with high and low levels of tumour-infiltrating Tregs (A) and exhausted CD8+ T cells (B). (C,D) The difference in OS between patients with high and low levels of tumour-infiltrating Tregs (C) and exhausted CD8+ T cells (D).
