Table 3.
Association of a 1-Hour Treatment Delay with Different Outcomes at 90 Days in Patients Treated With Endovascular Therapy
| Unadjusted OR per 1-hour delay (95% CI) | Unadjusted ARD, % (95% CI) | Model 1 | Model 2 | |||
|---|---|---|---|---|---|---|
| aOR per 1-hour delay (95% CI)* | aARD, % (95% CI)* | aOR per 1-hour delay (95% CI)* | aARD, % (95% CI)* | |||
| Onset to reperfusion | ||||||
| mRS 0–1 | 0.89 (0.82 to 0.97) | −2.8 (−4.7 to −0.9) | 0.89 (0.80 to 0.99) | −2.1 (−3.8 to −0.3) | 0.89 (0.80 to 0.99) | −1.9 (−3.7 to −0.2) |
| mRS 0–2 | 0.89 (0.82 to 0.96) | −2.8 (−4.5 to −1.0) | 0.88 (0.79 to 0.98) | −1.9 (−3.5 to −0.4) | 0.89 (0.79 to 0.99) | −1.8 (−3.3 to −0.2) |
| mRS 0–3 | 0.90 (0.83 to 0.98) | −2.2 (− 3.8 to −0.5) | 0.90 (0.81 to 0.99) | −1.7 (− 3.2 to −0.2) | 0.91 (0.82 to 1.01) | −1.4 (− 2.9 to 0.1) |
ARD indicates absolute risk difference; aARD, adjusted absolute risk difference; aOR, adjusted odds ratio; FI, final infarct; mRS, modified Rankin Scale; and OR, odds ratio.
Adjusted ORs and absolute risk differences in predicted probabilities by hour were estimated from logistic regressions. The study adjusted for age, sex, stroke severity as baseline National Institutes of Health Stroke scale, prestroke mRS, location of occlusion, and additionally for final infarct as FIASPECTS at 24—48 hours in Model 1 and for FIVOLUME final infarct volume in Model 2.