Table 1.
Time Interval between Discontinuation of Pazopanib and Resolution of PRES Symptoms | Time Interval between Initiation of Pazopanib and PRES | Dose | Primary Cancer | Age/Gender | Author |
---|---|---|---|---|---|
1 day | 21 days | Not specified | RCC | 40/F | Chelis et al. [4] |
6 days | 8 weeks | 800 mg/day | RCC | 63/F | Foerster et al. [22] |
2 days | 4 weeks | Not specified | RCC | 76/M | Asaithambi et al. [23] |
Not specified | 3 weeks | Not specified | RCC | 69/F | Miller-Patterson et al. [24] |
60 h | 16–20 weeks | 400 mg/day | Testicular tumour | 32/M | Arslan et al. [25] |
3 days | 9 days | 800 mg/day | RCC | 56/F | Miaris et al. [26] |
5 days | 5–6 weeks | 800 mg/day | Retroperitoneal soft tissue sarcoma | 49/F | Deguchi et al. [27] |
5 days | 4 days | 800 mg/day | HCC | 76/F | Wu et al. [28] |
5 days | 20 months | Not specified | Hurthel cell thyroid carcinoma | 56/F | Koleszar et al. [29] |
9 days | 4 days | Not specified | Uterine sarcoma | 64/F | Takahashi et al. [30] |
6 days | 12 days | 600 mg/day | RCC | 73/F | Wong So et al. [31] |
7 days | 3 days | 800 mg/day | Uterine sarcoma | 64/F | Tatsumichi et al. [32] |
Abbreviation: F, Female; M, Male; PRES, posterior reversible encephalopathy syndrome; RCC, renal cell carcinoma; HCC, hepato-cellular carcinoma.