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. 2023 May 23;11(2):76. doi: 10.3390/diseases11020076

Table 1.

List of reported cases of pazopanib-induced PRES.

Time Interval between Discontinuation of Pazopanib and Resolution of PRES Symptoms Time Interval between Initiation of Pazopanib and PRES Dose Primary Cancer Age/Gender Author
1 day 21 days Not specified RCC 40/F Chelis et al. [4]
6 days 8 weeks 800 mg/day RCC 63/F Foerster et al. [22]
2 days 4 weeks Not specified RCC 76/M Asaithambi et al. [23]
Not specified 3 weeks Not specified RCC 69/F Miller-Patterson et al. [24]
60 h 16–20 weeks 400 mg/day Testicular tumour 32/M Arslan et al. [25]
3 days 9 days 800 mg/day RCC 56/F Miaris et al. [26]
5 days 5–6 weeks 800 mg/day Retroperitoneal soft tissue sarcoma 49/F Deguchi et al. [27]
5 days 4 days 800 mg/day HCC 76/F Wu et al. [28]
5 days 20 months Not specified Hurthel cell thyroid carcinoma 56/F Koleszar et al. [29]
9 days 4 days Not specified Uterine sarcoma 64/F Takahashi et al. [30]
6 days 12 days 600 mg/day RCC 73/F Wong So et al. [31]
7 days 3 days 800 mg/day Uterine sarcoma 64/F Tatsumichi et al. [32]

Abbreviation: F, Female; M, Male; PRES, posterior reversible encephalopathy syndrome; RCC, renal cell carcinoma; HCC, hepato-cellular carcinoma.