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Subgroup analysis comparing overall survival between patients in the sequential treatment and in the non-sequential treatment with trifluridine/tipiracil and regorafenib groups stratified by baseline characteristics. Abbreviations: HR, hazard ratio; PS, performance status; T, trifluridine/tipiracil, R, regorafenib; mets, metastases; wt, wild type; mt, mutant type; 95% CI, 95% confidence interval; yrs, years.
