Table 1.
Sorafenib Plasma Concentration ng/mL | p-Value of Embolized Area vs. Plasma | Sorafenib Liver Homogenate of Embolized Area ng/mL | p-Value of Embolized vs. Non-Embolized Area | Sorafenib Liver Homogenate of Non-Embolized Area ng/mL | p-Value of Non-Embolized Area vs. Plasma | |
---|---|---|---|---|---|---|
1 h | 139.7 (107.3) | 0.003 | 1534.5 (1249.4) | 0.28 | 1080.4 (1343.9) | 0.03 |
24 h | 63.5 (37.7) | 0.005 | 731.8 (528.5) | 0.07 | 306.8 (290.7) | 0.03 |
72 h | 13.2 (8.6) | 0.05 | 1233.4 (1326.6) | 0.007 | 98.9 (56.5) | 0.006 |