Table 1.
Clinically Significant MRI Finding 1 N = 53 |
No Significant MRI Finding N = 274 |
p-Value 2 | |
---|---|---|---|
Sex | N (%) | ||
Female | 39 (74) | 235 (86) | 0.027 |
Male | 14 (26) | 39 (14) | |
Age | Median (IQR) | ||
Total (years) | 28 (21–42) | 30 (23–38) | 0.957 |
Female (years) | 29 (24–42) | 29 (23–37) | 0.585 |
Male (years) | 24 (16–61) | 33 (22–45) | 0.545 |
Body mass index | Data available (N): Median (IQR) | ||
BMI (kg/m2) | 41:28 (24–36) |
181:25 (22–30) |
0.018 |
Medical risk factors | N (%) | ||
Smoking | 14 (26) | 54 (20) | 0.271 |
Thrombophilia | 1 (2) | 6 (2) | 0.889 |
Oral contraception | 7 (13) | 44 (16) | 0.601 |
Pregnancy | 1 (2) | 39 (14) | 0.012 |
Puerperium | 0 (0) | 11 (4) | 0.138 |
Symptoms | N (%) | ||
Headache | 47 (89) | 250 (91) | 0.554 |
Nausea/vomiting | 23 (43) | 122 (45) | 0.880 |
Visual impairment | 17 (32) | 91 (33) | 0.872 |
Numbness | 15 (28) | 82 (30) | 0.813 |
Vertigo | 13 (25) | 72 (26) | 0.790 |
Photophobia | 17 (32) | 61 (22) | 0.125 |
Neck muscle tension | 14 (26) | 57 (21) | 0.364 |
Dysphasia | 7 (13) | 34 (12) | 0.872 |
Seizure | 2 (4) | 6 (2) | 0.495 |
No other symptoms than headache | 2 (4) | 24 (9) | 0.219 |
Imaging information | N (%) | ||
Contrast-enhanced MRI | 48 (91) | 204 (75) | 0.011 |
Additional clinical information | Median (IQR) | ||
Duration of headache before MRI (days) | 4 (2–10) | 3 (1–10) | 0.097 |
Length of hospital stay (days) | 5 (0–9) | 0 (0–0) | <0.001 |
MRI = Magnetic resonance imaging, CVST = Cerebral venous sinus thrombosis, IQR = Interquartile range. 1 Including CVST. 2 p-Values are associated with Chi-squared test for categorical variables and with Wilcoxon rank sum test for continuous variables.