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. 2023 Jun 9;13(12):2018. doi: 10.3390/diagnostics13122018

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Incremental role of [⁶⁸Ga]Ga-FAPI-04 PET/CT over FDG PET/CT in a 42-year-old woman with metastatic gastric adenocarcinoma for post-chemotherapy response assessment. Baseline (A) and follow-up (C) FDG PET/CT scans did not reveal significant abnormal tracer uptake in the primary and metastatic lesions. Baseline [⁶⁸Ga]Ga-FAPI-04 PET/CT (B) showed tracer avid gastric primary (green arrow), abdominal lymph nodes (orange arrow), and solitary liver metastasis (red arrow). Post-chemotherapy [⁶⁸Ga]Ga-FAPI-04 PET/CT (D) demonstrated minimal tracer avidity in the gastric primary (green arrow) with resolution of tracer avidity in the abdominal lymph nodes (orange arrow) and liver lesion (red arrow), suggesting a favorable response to treatment.