Figure 6.

[⁶⁸Ga]Ga-FAPI-04 performed better than FDG PET/CT for initial staging in a 51-year-old woman with histopathologically proven triple receptor-negative invasive breast cancer. FDG PET/CT (A) revealed mildly tracer avid right breast primary ((C)—red arrow) with few faintly FDG avid right axillary lymph nodes ((A)—red arrow). FAPI PET/CT (B) demonstrated intensely tracer avid right breast primary ((D)—green arrow), multiple right axillary lymph nodes ((B)—green arrows), and few lytic skeletal lesions such as one involving the left transverse process of C2 vertebra ((F)—green arrow), which showed no abnormal FDG uptake ((E)—red arrow).