Figure 4.

Comparison of patients’ B lymphocyte subset values, calculated as normalized ratios, at four different time points according to days after hospital admission (0–5 and 6–16 days during hospitalization; 20–60 and >60 days at short- and long-term follow-up, respectively). (A): Total B lymphocyte counts. Percentages of different B cell subsets: (B) recent bone marrow emigrants (RBE); (C) naïve; (D) switched memory; (E) IgM+ unswitched memory; (F) CD21low cells; (G) terminally differentiated. Bars of the scatter dot plots represent medians and interquartile range. Statistical analyses between data for different time points were performed by the Mann-Whitney test. Horizontal bars among two groups indicate when p values were below 0.05. Pearson’s chi square test was performed to determine if data for each time point was significantly (p < 0.05) lower (down arrows) or higher (up arrows) from the normalized median (=1).