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. 2023 Jun 8;45(6):5018–5035. doi: 10.3390/cimb45060319

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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PAC promotes the effect of cisplatin on the inhibition of oxidative stress in oral cancer cells. (A) The quantification of ROS in flow cytometry (n = 4) showed inhibition when the Ca9-22 cells were treated with PAC and cisplatin for 24 h. The pink peak represents the % of ROS⁺ cells, and the blue peak is the percentage of ROS⁻ cells. (B) MitoSox expression performed by flow cytometry (n = 4). ** p < 0.005 *** p < 0.0005 compared to untreated cells.

PAC promotes the effect of cisplatin on the inhibition of oxidative stress in oral cancer cells. (A) The quantification of ROS in flow cytometry (n = 4) showed inhibition when the Ca9-22 cells were treated with PAC and cisplatin for 24 h. The pink peak represents the % of ROS⁺ cells, and the blue peak is the percentage of ROS⁻ cells. (B) MitoSox expression performed by flow cytometry (n = 4). ** p < 0.005 *** p < 0.0005 compared to untreated cells.