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Growth inhibition of (A) MIA PaCa-2 cells, (B) NCI-H358 cells, (C) AGS cells, and (D) PA-TU-8988T cells after 3-day treatment with deltasonamide 2, MRTX849 (a KRASG12C inhibitor), FPFT-2216, TMX-4100, or TMX-4113. Both deltasonamide 2 and MRTX849 were dosed once, while FPFT-2216, TMX-4100, and TMX-4113 were dosed daily.
