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(a,b): HBME1 colloidal pattern of immunoreactivity restricted to the colloid of follicles with PLNF changes, associated with lymphocytic infiltrate. The HBME1 immunoreactivity pattern is different from the membranous HBME1 pattern seen in thyrocytes of PTC, which is shown for comparison in (c). (HBME1 immunostaining, (a): 40×; (b): 200× (c): 400×).
