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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: J Allergy Clin Immunol. 2023 Mar 4;151(6):1660–1666.e4. doi: 10.1016/j.jaci.2023.02.025

FIG 3.

FIG 3.

AD-like skin phenotype is alleviated in TSLPR-deficient mice. (A) Protocol. (B) TEWL was measured 24 hours after patch removal (n = 5–20 mice per group from 2 separate experiments; significance assessed by 2-way ANOVA). (C) Representative pictures taken 24 hours after removal of third patch. (D) Representative skin section of toluidine blue–stained mast cells. Epidermal thickness was measured by Image Pro Plus 4.1. (E) OVA-specific IgE blood levels. (F) Number of dermal eosinophils per HPF (original magnification ×40). (G) Amount of surface IgE on mast cells was determined by MFI on lineage-negative cKit+IgE+ skin cells. (H) Blood levels of MCPT1 after third patch. Significance was assessed by 1-way ANOVA (*P < .05, **P < .01, ***P < .001, ****P < .0001, ns = not significant). HPF, High-power field; MFI, mean fluorescent intensity.