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. 2023 Jun 12;24(12):10015. doi: 10.3390/ijms241210015

Figure 1.

Figure 1

NR supplementation prevents obesity-related metabolic abnormalities in HFD-fed mice. Mice were fed with an HFD ± NR supplementation for 24 weeks. (A) Body weight in the indicated groups. (B) Fat body mass was determined via visceral adiposity index. (C) Body composition imaging of mice, the yellow part is the fat. (D) Serum LDL-C contents. (E) Serum TC contents. (F) Liver TC contents. (G) Liver TG contents. (H) H&E staining of liver, WAT, BAT. For the H&E staining of liver and WAT, the microscope magnification is 200×. For the H&E staining of WAT and BAT, the microscope magnification is 400×. n = 5–7 in each group. * p < 0.05 compared with the CON group; # p < 0.05 comparing HFD group vs. HFD + NR group. Abbreviations: CON—control group; HFD—high-fat diet group, HFD + NR—high-fat diet + nicotinamide riboside group; LDL-C—low-density-lipoprotein cholesterol; TC—total cholesterol; TG—triglyceride; H&E staining—hematoxylin–eosin staining; WAT—white adipose tissue; BAT—brown adipose tissue.