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. 2023 Jun 12;24(12):10015. doi: 10.3390/ijms241210015

Figure 2.

Figure 2

NR supplementation alleviates insulin resistance in HFD-fed mice. (A) Fasting blood glucose levels. (B) Fasting blood insulin levels. (C) HOMA-IR index. (D) Immunofluorescence of insulin and glucagon in the islet of mice. Images were taken using a confocal microscope, the microscope magnification is 400×. (E,F) Representative IPGTT (E) and ITT (F) and the AUC result of mice in the indicated groups. n = 5–7 for each group. * p < 0.05 compared with the CON group; # p < 0.05 comparing HFD group vs. HFD + NR group. Abbreviations: FBG—fasting blood glucose levels; HOMA-IR index—homeostasis model assessment of insulin resistance index; IPGTT—intraperitoneal glucose tolerance test; ITT—insulin tolerance test; AUC—area under the curve.