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. 2023 Jun 12;24(12):10015. doi: 10.3390/ijms241210015

Figure 8.

Figure 8

AMPK activation is required for improvement of insulin sensitivity using NR in PA-treated skeletal muscle cells. (A) 2-NBDG uptake of C2C12 myotube cells in the indicated groups, the microscope magnification is 200×. (B) Representative Western blot results of insulin signaling pathway-associated protein (AKT) of cells. β-Actin served as a loading control. (C) Quantitative results for WB. * p < 0.05 compared with the CON group; # p < 0.05 comparing PA group vs. PA + NR group. & p < 0.05 PA + NR group vs. PA + NR + Compound C group.